MFAP1

Across TCGA cell cohorts, MFAP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,705 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MFAP1-associated GO terms across cancer lineages are Transcription elongation by RNA polymerase II, Microtubule nucleation, and Positive regulation of transcription initiation by RNA polymerase II. Each is linked with MFAP1 in more than 16 cancer types. Because this analysis shows association rather than direction, both MFAP1-to-partner and partner-to-MFAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transcription elongation by RNA polymerase II grouped by MFAP1-low versus MFAP1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MFAP1→partner) and Y-score (partner→MFAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Transcription elongation by RNA polymerase II →	+0.124	+0.633	.003	.004	3	17
SOFT_TISSUE	Microtubule nucleation →	+0.105	+0.678	<.001	.002	3	17
LARGE_INTESTINE	Positive regulation of transcription initiation by RNA polymerase II →	+0.073	+0.719	<.001	<.001	3	17
OVARY	Heterochromatin formation →	+0.060	+0.496	<.001	.002	3	15
LARGE_INTESTINE	Ubiquitin-dependent protein catabolic process via the N-end rule pathway →	+0.101	+0.774	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Negative regulation of cell cycle G2/M phase transition →	+0.070	+0.925	.003	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,705 associations by consensus.

Transcription elongation by RNA polymerase II by MFAP1 expression — OESOPHAGUS

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