MEX3A

Across TCGA pan-cancer cohorts, MEX3A mass-spec protein differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of MEX3A’s most consistent transcriptional readouts.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where MEX3A mass-spec protein is repressed in tumor relative to normal tissue. In most cancer types MEX3A is over-expressed in tumor, although a few such as CCRCC and LUAD show the opposite, repressed pattern.

CCRCC, LUAD, and OV are the cancer types where MEX3A tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MEX3A mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
CCRCC	All	IV	−2.056	<.001	12	view →
LUAD	Female	II,III,IV	−0.315	.010	3	view →
OV	All	All	−0.888	.014	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

MEX3A–CCRCC

Open the CCRCC breakdown →