MEX3A

Across TCGA cell cohorts, MEX3A mutation is significantly associated with the RNA expression of many other genes, with 69 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MEX3A-associated genes across cancer lineages are GPR101, IQCF1, and MMP27. Each is linked with MEX3A in more than 1 cancer types. Because this analysis shows association rather than direction, both MEX3A-to-partner and partner-to-MEX3A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GPR101 grouped by MEX3A-low versus MEX3A-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MEX3A→partner) and Y-score (partner→MEX3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	GPR101 →	+0.016	+4.990	<.001	.001	3	2
LARGE_INTESTINE	IQCF1 →	+0.155	+3.443	.005	.009	3	2
BLOOD_Leukemia	MMP27 →	+0.013	+3.969	<.001	.009	3	2
OVARY	OR2H1 →	+0.027	+4.029	<.001	.009	3	1
OVARY	GPX5 →	+0.016	+4.228	.007	.006	3	1
OVARY	OR12D2 →	+0.047	+4.700	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 69 associations by consensus.

GPR101 by MEX3A expression — OVARY

Explore this box plot interactively →