Across TCGA patient cohorts, METTL9 protein abundance is significantly associated with the RNA expression of many other genes, with 8,809 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible METTL9-associated genes across cancer lineages are PDXDC1, ALDOA, and NOMO2. Each is linked with METTL9 in more than 5 cancer types. Because this analysis shows association rather than direction, both METTL9-to-partner and partner-to-METTL9 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (METTL9→partner) and Y-score (partner→METTL9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PDXDC1 →	+0.510	+0.341	.004	.005	2	6
OV	ALDOA →	+0.690	+0.398	.001	.006	3	4
OV	NOMO2 →	+0.789	+0.448	.006	<.001	2	5
PDAC	UBFD1 →	+0.416	+0.374	<.001	<.001	3	4
HNSC	ARHGEF6 →	-0.937	-0.376	<.001	.002	3	4
LSCC	RFTN1 →	-0.644	-0.224	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,809 associations by consensus.

Exploration

METTL9 survival (RNA) · tumor vs normal (RNA) · all METTL9 data types