Across TCGA cell cohorts, METTL9 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,058 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible METTL9-associated GO terms across cancer lineages are Positive regulation of macrophage proliferation, Interleukin-34-mediated signaling pathway, and Symbiont-mediated disruption of host cell PML body. Each is linked with METTL9 in more than 11 cancer types. Because this analysis shows association rather than direction, both METTL9-to-partner and partner-to-METTL9 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (METTL9→partner) and Y-score (partner→METTL9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Positive regulation of macrophage proliferation →	+0.209	+0.962	<.001	<.001	3	12
SKIN	Interleukin-34-mediated signaling pathway →	+0.118	+1.026	<.001	<.001	3	11
LUNG_SCLC	Symbiont-mediated disruption of host cell PML body →	+0.124	+0.604	<.001	.008	3	10
UPPER_AERODIGESTIVE_TRACT	Regulation of macrophage proliferation →	+0.214	+1.032	.001	<.001	3	10
LUNG_NSCLC_LUSC	Cell maturation →	-0.067	-0.972	<.001	.001	3	9
UPPER_AERODIGESTIVE_TRACT	Regulation of G2/M transition of mitotic cell cycle →	+0.092	+0.976	.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,058 associations by consensus.

Exploration

METTL9 survival (RNA) · tumor vs normal (RNA) · all METTL9 data types