METTL7B

Across TCGA patient cohorts, METTL7B protein abundance is significantly associated with the RNA expression of many other genes, with 11,577 significant associations in total. GBM shows the largest number of these associations.

The most reproducible METTL7B-associated genes across cancer lineages are RDH5, GJB1, and LINC00870. Each is linked with METTL7B in more than 5 cancer types. Because this analysis shows association rather than direction, both METTL7B-to-partner and partner-to-METTL7B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, METTL7B versus RDH5 in OV, with a Pearson correlation of 0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (METTL7B→partner) and Y-score (partner→METTL7B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	RDH5 →	+0.763	+0.760	<.001	<.001	3	6
LUAD	GJB1 →	+1.540	+0.624	<.001	.001	3	5
CCRCC	LINC00870 →	+0.297	+0.508	.001	<.001	3	5
CCRCC	ABCC6P2 →	+0.912	+0.343	<.001	<.001	3	5
OV	SPR →	+0.789	+0.776	.002	<.001	3	4
COAD	BAG2 →	-0.684	-0.280	.004	.006	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,577 associations by consensus.

METTL7B vs RDH5 — OV

Explore this scatter interactively →