METTL7B

Across TCGA cell cohorts, METTL7B mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible METTL7B-associated genes across cancer lineages are MYF6 and OR5B3. Each is linked with METTL7B in more than 1 cancer types. Because this analysis shows association rather than direction, both METTL7B-to-partner and partner-to-METTL7B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYF6 grouped by METTL7B-low versus METTL7B-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (METTL7B→partner) and Y-score (partner→METTL7B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	MYF6 →	+0.028	+4.977	<.001	.007	3	1
SKIN	OR5B3 →	+0.038	+5.415	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

MYF6 by METTL7B expression — SKIN

Explore this box plot interactively →