Across TCGA patient cohorts, METTL7A mutation is significantly associated with the RNA expression of many other genes, with 607 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible METTL7A-associated genes across cancer lineages are H3Y1, MRPS16P1, and MIR1915. Each is linked with METTL7A in more than 1 cancer types. Because this analysis shows association rather than direction, both METTL7A-to-partner and partner-to-METTL7A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (METTL7A→partner) and Y-score (partner→METTL7A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	H3Y1 →	+0.838	+2.093	<.001	.009	3	2
BLCA	MRPS16P1 →	+0.111	+4.562	<.001	.006	3	2
COAD	MIR1915 →	+0.577	+4.893	<.001	.005	3	1
COAD	MAPK6P6 →	+0.127	+4.237	<.001	.008	3	1
COAD	RN7SL83P →	+0.534	+5.392	<.001	.002	3	1
COAD	BCAS2P1 →	+0.353	+4.951	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 607 associations by consensus.

Exploration

METTL7A survival (RNA) · tumor vs normal (RNA) · all METTL7A data types