Across TCGA patient cohorts, METTL7A mutation is significantly associated with the total protein of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible METTL7A-associated genes across cancer lineages are p27_pT157, S6_pS240_S244, and TAZ. Each is linked with METTL7A in more than 1 cancer types. Because this analysis shows association rather than direction, both METTL7A-to-partner and partner-to-METTL7A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (METTL7A→partner) and Y-score (partner→METTL7A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	p27_pT157 →	-0.082	-2.986	.007	.035	3	1
UCEC	S6_pS240_S244 →	+0.703	+3.321	<.001	.010	3	1
UCEC	TAZ →	-0.151	-3.321	.042	.010	3	1
UCEC	ATM →	-0.729	-3.321	.002	.010	3	1
UCEC	p62 Lck ligand →	+0.383	+3.321	.024	.010	2	1
UCEC	ARID1A →	-0.205	-3.162	.039	.019	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration

METTL7A survival (RNA) · tumor vs normal (RNA) · all METTL7A data types