METTL25

Across TCGA patient cohorts, METTL25 protein abundance is significantly associated with the RNA expression of many other genes, with 2,892 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible METTL25-associated genes across cancer lineages are ABLIM2, C15orf40, and LRRC37B. Each is linked with METTL25 in more than 2 cancer types. Because this analysis shows association rather than direction, both METTL25-to-partner and partner-to-METTL25 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, METTL25 versus ABLIM2 in OV, with a Pearson correlation of -0.60.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (METTL25→partner) and Y-score (partner→METTL25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ABLIM2 →	-0.871	-0.991	.008	.003	3	2
OV	C15orf40 →	-0.706	-0.940	<.001	.006	3	2
OV	LRRC37B →	-0.486	-0.935	.007	.007	3	2
PDAC	PCDHGA7 →	-0.817	-0.225	.005	.008	3	2
OV	CENATAC-DT →	-1.172	-1.377	.001	.005	3	2
GBM	FBXO24 →	+0.720	+0.869	.006	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,892 associations by consensus.

METTL25 vs ABLIM2 — OV

Explore this scatter interactively →