METTL21EP

Across TCGA patient cohorts, METTL21EP mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible METTL21EP-associated genes across cancer lineages are RN7SKP44, H3C15, and RNU6-147P. Each is linked with METTL21EP in more than 1 cancer types. Because this analysis shows association rather than direction, both METTL21EP-to-partner and partner-to-METTL21EP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP44 grouped by METTL21EP-low versus METTL21EP-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (METTL21EP→partner) and Y-score (partner→METTL21EP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SKP44 →	+0.240	+4.551	<.001	.009	3	1
UCEC	H3C15 →	+0.041	+4.484	<.001	.009	3	1
UCEC	RNU6-147P →	+0.553	+4.551	<.001	.009	3	1
UCEC	MIR1266 →	+0.572	+4.771	<.001	.006	3	1
UCEC	DPPA2P3 →	+0.233	+4.211	<.001	.009	3	1
UCEC	RNU7-125P →	+0.996	+4.690	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

RN7SKP44 by METTL21EP expression — UCEC

Explore this box plot interactively →