Across TCGA patient cohorts, METTL11B mutation is significantly associated with the RNA expression of many other genes, with 986 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible METTL11B-associated genes across cancer lineages are RPS10-NUDT3, ATP1B3P1, and POM121C. Each is linked with METTL11B in more than 1 cancer types. Because this analysis shows association rather than direction, both METTL11B-to-partner and partner-to-METTL11B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (METTL11B→partner) and Y-score (partner→METTL11B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RPS10-NUDT3 →	+0.220	+2.598	.004	.002	3	1
UCEC	ATP1B3P1 →	+0.213	+3.392	.007	.006	3	1
UCEC	POM121C →	+0.444	+1.960	.001	.009	3	1
UCEC	CWC25 →	+0.572	+3.512	<.001	.002	3	1
UCEC	ZNHIT3 →	+0.397	+3.608	.009	.001	3	1
UCEC	TAF9 →	+0.546	+2.415	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 986 associations by consensus.

Exploration

METTL11B survival (RNA) · tumor vs normal (RNA) · all METTL11B data types