Across TCGA cell cohorts, METTL11B mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible METTL11B-associated genes across cancer lineages are FTHL17, OR2J1, and DAZ4. Each is linked with METTL11B in more than 1 cancer types. Because this analysis shows association rather than direction, both METTL11B-to-partner and partner-to-METTL11B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (METTL11B→partner) and Y-score (partner→METTL11B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	FTHL17 →	+0.081	+5.415	<.001	.004	3	1
LARGE_INTESTINE	OR2J1 →	+0.006	+6.022	<.001	.001	3	1
LARGE_INTESTINE	DAZ4 →	+0.326	+4.977	<.001	.007	3	1
LARGE_INTESTINE	DAZ2 →	+0.336	+5.415	<.001	.004	3	1
LARGE_INTESTINE	RBMY1J →	+0.013	+6.022	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

METTL11B survival (RNA) · tumor vs normal (RNA) · all METTL11B data types