Across TCGA cell cohorts, METTL11B mutation is significantly associated with the mutation status of many other genes, with 686 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible METTL11B-associated genes across cancer lineages are GMPR, TRIM64C, and NAXD. Each is linked with METTL11B in more than 2 cancer types. Because this analysis shows association rather than direction, both METTL11B-to-partner and partner-to-METTL11B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (METTL11B→partner) and Y-score (partner→METTL11B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	GMPR →	+4.321	+5.285	.005	.005	1	3
LARGE_INTESTINE	TRIM64C →	+4.672	+5.329	<.001	<.001	1	2
BLOOD_Leukemia	NAXD →	+4.736	+5.560	.003	.003	1	2
BLOOD_Leukemia	TRIM26 →	+5.321	+5.894	.002	.002	1	2
BLOOD_Leukemia	FMC1-LUC7L2 →	+6.321	+6.321	.001	.001	1	2
LARGE_INTESTINE	RHOBTB2 →	+3.087	+4.392	.005	.005	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 686 associations by consensus.

Exploration

METTL11B survival (RNA) · tumor vs normal (RNA) · all METTL11B data types