METRNL

Across TCGA patient cohorts, METRNL RNA expression is significantly associated with the protein abundance of many other proteins, with 16,472 significant associations in total. GBM shows the largest number of these associations.

The most reproducible METRNL-associated proteins across cancer lineages are JUNB, C1QA, and RIN3. Each is linked with METRNL in more than 5 cancer types. Because this analysis shows association rather than direction, both METRNL-to-partner and partner-to-METRNL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, METRNL versus JUNB in LSCC, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (METRNL→partner) and Y-score (partner→METRNL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	JUNB →	+0.469	+0.706	<.001	<.001	3	6
CCRCC	C1QA →	+0.615	+0.751	<.001	<.001	3	6
COAD	RIN3 →	+0.427	+0.706	<.001	.001	3	6
GBM	PROS1 →	+0.624	+0.885	<.001	<.001	3	5
GBM	PPP1R18_S224 →	+0.588	+1.081	<.001	<.001	3	5
HNSC	IL1RN →	+0.965	+0.844	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,472 associations by consensus.

METRNL vs JUNB — LSCC

Explore this scatter interactively →