METAP2P1

Across TCGA patient cohorts, METAP2P1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,148 significant associations in total. STAD shows the largest number of these associations.

The most reproducible METAP2P1-associated GO terms across cancer lineages are Positive regulation of transcription elongation by RNA polymerase II, RNA 3'-end processing, and Regulation of proteolysis involved in protein catabolic process. Each is linked with METAP2P1 in more than 11 cancer types. Because this analysis shows association rather than direction, both METAP2P1-to-partner and partner-to-METAP2P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of transcription elongation by RNA polymerase II grouped by METAP2P1-low versus METAP2P1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (METAP2P1→partner) and Y-score (partner→METAP2P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of transcription elongation by RNA polymerase II →	+0.062	+0.080	<.001	<.001	3	12
STAD	RNA 3'-end processing →	+0.062	+0.080	<.001	<.001	3	10
STAD	Regulation of proteolysis involved in protein catabolic process →	+0.057	+0.067	<.001	<.001	3	10
STAD	Positive regulation of epithelial cell migration →	+0.047	+0.066	<.001	<.001	3	9
STAD	Regulation of protein ubiquitination →	+0.059	+0.069	<.001	<.001	3	9
STAD	Regulation of transcription elongation by RNA polymerase II →	+0.063	+0.069	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,148 associations by consensus.

Positive regulation of transcription elongation by RNA polymerase II by METAP2P1 expression — STAD

Explore this box plot interactively →