MESTP2

Across TCGA patient cohorts, MESTP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,081 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MESTP2-associated GO terms across cancer lineages are Positive regulation of binding, Regulation of proteasomal ubiquitin-dependent protein catabolic process, and Erythrocyte homeostasis. Each is linked with MESTP2 in more than 7 cancer types. Because this analysis shows association rather than direction, both MESTP2-to-partner and partner-to-MESTP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of binding grouped by MESTP2-low versus MESTP2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MESTP2→partner) and Y-score (partner→MESTP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of binding →	+0.054	+0.071	<.001	<.001	3	8
STAD	Regulation of proteasomal ubiquitin-dependent protein catabolic process →	+0.059	+0.068	<.001	<.001	3	8
STAD	Erythrocyte homeostasis →	+0.052	+0.067	<.001	<.001	3	8
STAD	Osteoblast differentiation →	+0.042	+0.063	<.001	<.001	3	7
STAD	Protein N-linked glycosylation via asparagine →	+0.055	+0.061	<.001	<.001	3	7
STAD	Positive regulation of ATP-dependent activity →	+0.048	+0.069	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,081 associations by consensus.

Positive regulation of binding by MESTP2 expression — STAD

Explore this box plot interactively →