Across TCGA cell cohorts, MESP2 mutation is significantly associated with the drug of many other genes, with 10 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MESP2-associated genes across cancer lineages are 150412, Palbociclib, and 123829. Each is linked with MESP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MESP2-to-partner and partner-to-MESP2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MESP2→partner) and Y-score (partner→MESP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	150412 →	+0.431	+2.777	.009	.038	3	1
LARGE_INTESTINE	Palbociclib →	+0.590	+2.646	.015	.047	2	1
LARGE_INTESTINE	123829 →	+0.652	+2.649	.024	.046	2	1
LARGE_INTESTINE	741909 →	+0.576	+2.649	.030	.046	2	1
LARGE_INTESTINE	Dinaciclib →	+0.558	+2.646	.030	.047	1	1
LARGE_INTESTINE	IWP-2 →	+0.280	+2.893	.036	.034	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

Exploration

MESP2 survival (RNA) · tumor vs normal (RNA) · all MESP2 data types