MEP1A

Across TCGA cell cohorts, MEP1A RNA expression is significantly associated with the go_rna of many other GO terms, with 1,451 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MEP1A-associated GO terms across cancer lineages are Regulation of mRNA catabolic process, Regulation of RNA stability, and Regulation of mRNA stability. Each is linked with MEP1A in more than 4 cancer types. Because this analysis shows association rather than direction, both MEP1A-to-partner and partner-to-MEP1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mRNA catabolic process grouped by MEP1A-low versus MEP1A-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MEP1A→partner) and Y-score (partner→MEP1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Regulation of mRNA catabolic process →	+0.076	+0.237	<.001	.006	3	5
SOFT_TISSUE	Regulation of RNA stability →	+0.082	+0.236	<.001	.006	3	5
SOFT_TISSUE	Regulation of mRNA stability →	+0.082	+0.236	<.001	.006	3	5
LARGE_INTESTINE	Bundle of His cell to Purkinje myocyte communication →	+0.205	+1.245	<.001	.001	3	5
SOFT_TISSUE	Positive regulation of lipase activity →	-0.138	-0.174	.003	.009	3	4
URINARY_TRACT	Transepithelial water transport →	+1.228	+0.020	.004	.003	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,451 associations by consensus.

Regulation of mRNA catabolic process by MEP1A expression — SOFT_TISSUE

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