MEOX1

Across TCGA cell cohorts, MEOX1 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible MEOX1-associated genes across cancer lineages are CELA1, OR10T2, and PRAMEF10. Each is linked with MEOX1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MEOX1-to-partner and partner-to-MEOX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CELA1 grouped by MEOX1-low versus MEOX1-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MEOX1→partner) and Y-score (partner→MEOX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	CELA1 →	+0.035	+4.643	<.001	.004	3	1
LUNG_SCLC	OR10T2 →	+0.177	+4.044	<.001	.009	3	1
LUNG_SCLC	PRAMEF10 →	+0.885	+4.643	<.001	.004	3	1
LUNG_SCLC	FAM25G →	+0.648	+4.269	<.001	.005	3	1
LUNG_SCLC	PRAMEF20 →	+0.367	+4.269	<.001	.005	3	1
LUNG_SCLC	PRAMEF17 →	+0.010	+4.643	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

CELA1 by MEOX1 expression — LUNG_SCLC

Explore this box plot interactively →