MEMO1

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MEMO1 mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MEMO1-associated genes across cancer lineages are Myocytes, CMP, and Erythrocytes. Each is linked with MEMO1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MEMO1-to-partner and partner-to-MEMO1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Myocytes grouped by MEMO1-low versus MEMO1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MEMO1→partner) and Y-score (partner→MEMO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMyocytes →+0.037+3.076.006.01632
LUADCMP →+0.023+3.577.019.01531
LUADErythrocytes →+0.037+3.191<.001.03131
COADCD4+ Tcm →+0.003+5.741.024.02331
UCECAdipocytes →+0.019+1.770.010.02231
Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Myocytes by MEMO1 expression — UCEC

Box plot of Myocytes in MEMO1-low vs MEMO1-high samples in UCEC.

Explore this box plot interactively →

Exploration