MEMO1

Across TCGA cell cohorts, MEMO1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,299 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible MEMO1-associated GO terms across cancer lineages are Protein localization to kinetochore, Centromeric sister chromatid cohesion, and Regulation of chromosome separation. Each is linked with MEMO1 in more than 11 cancer types. Because this analysis shows association rather than direction, both MEMO1-to-partner and partner-to-MEMO1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to kinetochore grouped by MEMO1-low versus MEMO1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MEMO1→partner) and Y-score (partner→MEMO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Protein localization to kinetochore →	+0.181	+1.099	<.001	<.001	3	12
LUNG_NSCLC_LUAD	Centromeric sister chromatid cohesion →	+0.131	+0.604	<.001	<.001	3	12
KIDNEY	Regulation of chromosome separation →	+0.147	+0.798	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	DNA replication checkpoint signaling →	+0.197	+1.050	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Positive regulation of cell cycle process →	+0.103	+0.955	<.001	<.001	3	10
URINARY_TRACT	Purine deoxyribonucleoside monophosphate biosynthetic process →	+0.116	+0.586	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,299 associations by consensus.

Protein localization to kinetochore by MEMO1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →