MEIS3

Across TCGA patient cohorts, MEIS3 protein abundance is significantly associated with the RNA expression of many other genes, with 537 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible MEIS3-associated genes across cancer lineages are RNASEH2A, KLK14, and TPBG. Each is linked with MEIS3 in more than 1 cancer types. Because this analysis shows association rather than direction, both MEIS3-to-partner and partner-to-MEIS3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MEIS3 versus RNASEH2A in COAD, with a Pearson correlation of -0.92.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MEIS3→partner) and Y-score (partner→MEIS3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNASEH2A →	-0.385	-0.669	.002	.005	3	1
COAD	KLK14 →	-0.480	-0.623	<.001	.003	3	1
COAD	TPBG →	-2.574	-0.669	.009	.005	3	1
COAD	ADAMTS15 →	-3.584	-0.669	.003	.005	3	1
COAD	DDN →	-1.754	-0.669	.005	.005	3	1
COAD	MIR125B1 →	-2.153	-0.445	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 537 associations by consensus.

MEIS3 vs RNASEH2A — COAD

Explore this scatter interactively →