MEIS3

Across TCGA cell cohorts, MEIS3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,235 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MEIS3-associated GO terms across cancer lineages are Postsynaptic density protein 95 clustering, Thigmotaxis, and Response to starvation. Each is linked with MEIS3 in more than 10 cancer types. Because this analysis shows association rather than direction, both MEIS3-to-partner and partner-to-MEIS3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Postsynaptic density protein 95 clustering grouped by MEIS3-low versus MEIS3-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MEIS3→partner) and Y-score (partner→MEIS3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Postsynaptic density protein 95 clustering →	+1.448	+3.050	.001	<.001	3	11
OESOPHAGUS	Thigmotaxis →	+0.307	+1.931	.008	<.001	3	11
STOMACH	Response to starvation →	+0.073	+3.184	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Regulation of myoblast fusion →	+0.097	+1.459	<.001	<.001	3	11
STOMACH	Negative regulation of myoblast fusion →	+0.166	+2.818	<.001	.001	3	11
STOMACH	Negative regulation of syncytium formation by plasma membrane fusion →	+0.164	+2.633	<.001	.002	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,235 associations by consensus.

Postsynaptic density protein 95 clustering by MEIS3 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →