MEIOC

Across TCGA patient cohorts, MEIOC mutation is significantly associated with the RNA expression of many other genes, with 2,840 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MEIOC-associated genes across cancer lineages are AKR1B1P3, HNRNPA1P63, and LINC01029. Each is linked with MEIOC in more than 1 cancer types. Because this analysis shows association rather than direction, both MEIOC-to-partner and partner-to-MEIOC results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AKR1B1P3 grouped by MEIOC-low versus MEIOC-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MEIOC→partner) and Y-score (partner→MEIOC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	AKR1B1P3 →	+0.192	+3.827	<.001	<.001	3	2
COAD	HNRNPA1P63 →	+0.218	+3.730	<.001	.004	3	2
COAD	LINC01029 →	+0.129	+2.958	.009	.007	3	2
UCEC	ALDOA →	+0.390	+1.584	.004	.005	3	2
UCEC	PANK4 →	+0.365	+3.053	<.001	<.001	3	2
UCEC	ABHD3 →	+0.488	+1.928	.003	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,840 associations by consensus.

AKR1B1P3 by MEIOC expression — COAD

Explore this box plot interactively →