MEIKIN

Across TCGA cell cohorts, MEIKIN RNA expression is significantly associated with the mutation status of many other genes, with 117 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible MEIKIN-associated genes across cancer lineages are SPATA6, CCNF, and PCDHGB4. Each is linked with MEIKIN in more than 1 cancer types. Because this analysis shows association rather than direction, both MEIKIN-to-partner and partner-to-MEIKIN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SPATA6 grouped by MEIKIN-low versus MEIKIN-high in BONE.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MEIKIN→partner) and Y-score (partner→MEIKIN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	SPATA6 →	+4.169	+0.037	.008	<.001	3	2
URINARY_TRACT	CCNF →	+4.087	+0.357	.009	<.001	3	2
URINARY_TRACT	PCDHGB4 →	+5.087	+0.476	.004	<.001	3	2
LIVER	FLG2 →	+3.459	+0.036	.004	.001	3	2
SKIN	PEX6 →	+4.415	+0.017	.007	<.001	3	2
BLOOD_Myeloma	H1-5 →	+4.807	+0.176	.006	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 117 associations by consensus.

SPATA6 by MEIKIN expression — BONE

Explore this box plot interactively →