Across TCGA patient cohorts, MEIG1 mutation is significantly associated with the total protein of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MEIG1-associated genes across cancer lineages are eEF2, Heregulin, and eIF4G. Each is linked with MEIG1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MEIG1-to-partner and partner-to-MEIG1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MEIG1→partner) and Y-score (partner→MEIG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.428	+3.000	.038	.037	3	1
UCEC	Heregulin →	-0.163	-3.000	.022	.037	3	1
UCEC	eIF4G →	+0.390	+3.000	.029	.037	1	1
UCEC	ERK2 →	+0.273	+3.000	.014	.037	1	1
UCEC	HER3 →	-0.359	-2.986	.023	.037	1	1
UCEC	MEK1 →	+0.477	+3.000	.024	.037	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration

MEIG1 survival (RNA) · tumor vs normal (RNA) · all MEIG1 data types