MEI1

Across TCGA cell cohorts, MEI1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,616 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MEI1-associated GO terms across cancer lineages are Antigen processing and presentation of exogenous peptide antigen via MHC class Ib, Dephosphorylation, and Lagging strand elongation. Each is linked with MEI1 in more than 7 cancer types. Because this analysis shows association rather than direction, both MEI1-to-partner and partner-to-MEI1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Antigen processing and presentation of exogenous peptide antigen via MHC class Ib grouped by MEI1-low versus MEI1-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MEI1→partner) and Y-score (partner→MEI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Antigen processing and presentation of exogenous peptide antigen via MHC class Ib →	+0.223	+0.871	<.001	.001	3	8
SOFT_TISSUE	Dephosphorylation →	+0.030	+1.128	.006	.002	3	7
SOFT_TISSUE	Lagging strand elongation →	-0.136	-1.197	<.001	.001	3	6
SOFT_TISSUE	Striated muscle contraction →	+0.065	+0.762	<.001	.001	3	6
SOFT_TISSUE	Cellular response to UV-B →	+0.146	+0.960	<.001	<.001	3	6
OESOPHAGUS	Protein localization to extracellular region →	+0.094	+0.515	.001	.007	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,616 associations by consensus.

Antigen processing and presentation of exogenous peptide antigen via MHC class Ib by MEI1 expression — PANCREAS

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