MEGF9

Across TCGA patient cohorts, MEGF9 protein abundance is significantly associated with the RNA expression of many other genes, with 12,799 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible MEGF9-associated genes across cancer lineages are SETD7, MFSD6, and IFT27. Each is linked with MEGF9 in more than 4 cancer types. Because this analysis shows association rather than direction, both MEGF9-to-partner and partner-to-MEGF9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MEGF9 versus SETD7 in BRCA, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MEGF9→partner) and Y-score (partner→MEGF9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SETD7 →	+0.623	+0.408	<.001	<.001	3	5
HNSC	MFSD6 →	+0.940	+0.680	.001	.001	3	5
UCEC	IFT27 →	+0.556	+0.401	<.001	.001	3	4
UCEC	ABITRAM →	+0.499	+0.496	.002	.001	3	4
HNSC	ARHGEF26 →	+1.437	+0.521	<.001	<.001	3	4
HNSC	PCYOX1 →	+0.849	+0.660	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,799 associations by consensus.

MEGF9 vs SETD7 — BRCA

Explore this scatter interactively →