MEGF9

Across TCGA patient cohorts, MEGF9 mutation is significantly associated with the RNA expression of many other genes, with 3,801 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MEGF9-associated genes across cancer lineages are LINC00709, RPS6P20, and LINC01794. Each is linked with MEGF9 in more than 2 cancer types. Because this analysis shows association rather than direction, both MEGF9-to-partner and partner-to-MEGF9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC00709 grouped by MEGF9-low versus MEGF9-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MEGF9→partner) and Y-score (partner→MEGF9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	LINC00709 →	+0.075	+4.821	.005	.003	3	3
COAD	RPS6P20 →	+0.223	+3.259	<.001	.005	3	2
COAD	LINC01794 →	+0.075	+5.412	.007	.001	3	2
COAD	RNU6-693P →	+0.256	+4.399	<.001	.006	3	2
COAD	RNU7-53P →	+0.342	+4.399	.009	.006	3	2
COAD	HMGN1P28 →	+0.330	+3.537	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,801 associations by consensus.

LINC00709 by MEGF9 expression — COAD

Explore this box plot interactively →