MEGF9

Across TCGA cell cohorts, MEGF9 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,517 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MEGF9-associated GO terms across cancer lineages are Regulation of nucleotide-excision repair, Protein polyubiquitination, and Response to vitamin E. Each is linked with MEGF9 in more than 7 cancer types. Because this analysis shows association rather than direction, both MEGF9-to-partner and partner-to-MEGF9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of nucleotide-excision repair grouped by MEGF9-low versus MEGF9-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MEGF9→partner) and Y-score (partner→MEGF9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Regulation of nucleotide-excision repair →	+0.087	+0.703	<.001	<.001	3	8
KIDNEY	Protein polyubiquitination →	+0.042	+1.655	<.001	<.001	3	7
LIVER	Response to vitamin E →	+0.176	+1.578	.006	.008	3	7
KIDNEY	Vesicle localization →	+0.039	+1.551	.005	.001	3	7
PANCREAS	Exocytosis →	+0.057	+1.284	<.001	<.001	3	7
LUNG_NSCLC_LUAD	Response to platinum ion →	+0.102	+1.286	.002	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,517 associations by consensus.

Regulation of nucleotide-excision repair by MEGF9 expression — BLOOD_Leukemia

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