MEGF8

Across TCGA patient cohorts, MEGF8 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,897 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible MEGF8-associated proteins across cancer lineages are PAFAH1B3, SARM1, and COL5A1. Each is linked with MEGF8 in more than 6 cancer types. Because this analysis shows association rather than direction, both MEGF8-to-partner and partner-to-MEGF8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MEGF8 versus PAFAH1B3 in OV, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MEGF8→partner) and Y-score (partner→MEGF8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PAFAH1B3 →	+0.442	+0.862	.007	.009	2	7
BRCA	SARM1 →	+0.397	+0.474	.002	.002	3	4
HNSC	COL5A1 →	+0.680	+0.530	.002	.009	3	4
LUAD	IRGQ →	+0.369	+0.605	<.001	<.001	3	4
HNSC	MINK1 →	-0.404	-0.759	<.001	<.001	3	4
GBM	STRN4 →	+0.230	+0.580	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,897 associations by consensus.

MEGF8 vs PAFAH1B3 — OV

Explore this scatter interactively →