MEGF6

Across TCGA patient cohorts, MEGF6 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,902 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible MEGF6-associated proteins across cancer lineages are COMP, CTHRC1, and FBLN1. Each is linked with MEGF6 in more than 6 cancer types. Because this analysis shows association rather than direction, both MEGF6-to-partner and partner-to-MEGF6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MEGF6 versus COMP in OV, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MEGF6→partner) and Y-score (partner→MEGF6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	COMP →	+1.025	+0.992	.001	.002	3	7
OV	CTHRC1 →	+1.110	+1.255	<.001	<.001	3	6
OV	FBLN1 →	+0.617	+0.906	<.001	<.001	3	6
BRCA	HMCN1 →	+0.684	+1.211	<.001	<.001	3	6
BRCA	ISLR →	+0.655	+1.032	<.001	<.001	3	5
BRCA	PHLDA3 →	+0.580	+1.030	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,902 associations by consensus.

MEGF6 vs COMP — OV

Explore this scatter interactively →