MEGF6

Across TCGA patient cohorts, MEGF6 protein abundance is significantly associated with the RNA expression of many other genes, with 9,656 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible MEGF6-associated genes across cancer lineages are AEBP1, CCN2, and SCUBE2. Each is linked with MEGF6 in more than 5 cancer types. Because this analysis shows association rather than direction, both MEGF6-to-partner and partner-to-MEGF6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MEGF6 versus AEBP1 in COAD, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MEGF6→partner) and Y-score (partner→MEGF6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	AEBP1 →	+1.945	+0.929	<.001	<.001	3	6
OV	CCN2 →	+1.472	+0.929	<.001	<.001	3	6
BRCA	SCUBE2 →	+1.943	+0.515	<.001	<.001	3	6
OV	TMEM119 →	+1.437	+1.000	<.001	<.001	3	6
OV	LHFPL6 →	+1.066	+0.760	<.001	<.001	3	6
COAD	PRELP →	+1.678	+0.859	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,656 associations by consensus.

MEGF6 vs AEBP1 — COAD

Explore this scatter interactively →