MEGF10

Across TCGA patient cohorts, MEGF10 protein abundance is significantly associated with the RNA expression of many other genes, with 2,082 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MEGF10-associated genes across cancer lineages are PCYT1B, THRA, and ETNK2. Each is linked with MEGF10 in more than 1 cancer types. Because this analysis shows association rather than direction, both MEGF10-to-partner and partner-to-MEGF10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MEGF10 versus PCYT1B in LSCC, with a Pearson correlation of 0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MEGF10→partner) and Y-score (partner→MEGF10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PCYT1B →	+1.191	+1.147	<.001	<.001	3	2
GBM	THRA →	+0.653	+0.540	<.001	.001	3	2
BRCA	ETNK2 →	+1.433	+1.207	<.001	.002	3	2
LSCC	L3MBTL4 →	+1.092	+1.042	<.001	<.001	3	2
LSCC	CITED2 →	-0.688	-1.130	<.001	<.001	3	2
GBM	TEF →	+0.933	+0.716	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,082 associations by consensus.

MEGF10 vs PCYT1B — LSCC

Explore this scatter interactively →