MEGF10

Across TCGA cell cohorts, MEGF10 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,014 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible MEGF10-associated GO terms across cancer lineages are Skeletal muscle satellite cell activation, Cytoplasmic translation, and Regulation of syncytium formation by plasma membrane fusion. Each is linked with MEGF10 in more than 6 cancer types. Because this analysis shows association rather than direction, both MEGF10-to-partner and partner-to-MEGF10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Skeletal muscle satellite cell activation grouped by MEGF10-low versus MEGF10-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MEGF10→partner) and Y-score (partner→MEGF10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Skeletal muscle satellite cell activation →	+1.125	+2.664	<.001	<.001	3	7
SOFT_TISSUE	Cytoplasmic translation →	+0.076	+2.897	<.001	<.001	3	6
BONE	Regulation of syncytium formation by plasma membrane fusion →	+0.069	+0.576	.002	.005	3	6
CNS	Oxidative phosphorylation →	+0.064	+0.949	.003	.003	2	7
SOFT_TISSUE	RNA polymerase II preinitiation complex assembly →	+0.060	+1.977	<.001	.001	3	5
SOFT_TISSUE	Mammary gland epithelium development →	-0.102	-1.402	<.001	.006	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,014 associations by consensus.

Skeletal muscle satellite cell activation by MEGF10 expression — SOFT_TISSUE

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