MEFV

Across TCGA patient cohorts, MEFV protein abundance is significantly associated with the RNA expression of many other genes, with 10,611 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MEFV-associated genes across cancer lineages are FCAR, SOD2, and CXCL1. Each is linked with MEFV in more than 4 cancer types. Because this analysis shows association rather than direction, both MEFV-to-partner and partner-to-MEFV results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MEFV versus FCAR in GBM, with a Pearson correlation of 0.79.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MEFV→partner) and Y-score (partner→MEFV) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	FCAR →	+2.068	+1.594	.007	.008	3	5
BRCA	SOD2 →	+1.146	+1.136	.001	.008	3	4
LSCC	CXCL1 →	+1.840	+0.548	<.001	<.001	3	4
BRCA	CGAS →	+1.165	+1.589	<.001	<.001	3	4
GBM	MXD1 →	+1.035	+1.084	.003	.002	3	4
UCEC	CSF3R →	+1.767	+1.722	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,611 associations by consensus.

MEFV vs FCAR — GBM

Explore this scatter interactively →