MEFV

Across TCGA cell cohorts, MEFV RNA expression is significantly associated with the go_rna of many other GO terms, with 1,364 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MEFV-associated GO terms across cancer lineages are Action potential, Regulation of vacuole organization, and Regulation of telomere maintenance via telomere lengthening. Each is linked with MEFV in more than 6 cancer types. Because this analysis shows association rather than direction, both MEFV-to-partner and partner-to-MEFV results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Action potential grouped by MEFV-low versus MEFV-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MEFV→partner) and Y-score (partner→MEFV) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Action potential →	-0.039	-0.195	.008	.003	2	7
BLOOD_Leukemia	Regulation of vacuole organization →	+0.039	+1.015	.001	.001	3	5
BLOOD_Myeloma	Regulation of telomere maintenance via telomere lengthening →	+0.042	+0.162	.008	.005	2	5
BLOOD_Myeloma	Positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled →	+0.064	+0.131	.005	.005	2	5
BLOOD_Myeloma	Sensory perception of sound →	-0.029	-0.140	<.001	.002	3	4
CNS	Complement-mediated synapse pruning →	+1.024	+0.231	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,364 associations by consensus.

Action potential by MEFV expression — CNS

Explore this box plot interactively →