MEF2B

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MEF2B mutation is significantly associated with the RNA expression of many other genes, with 428 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MEF2B-associated genes across cancer lineages are RNA5SP281, RN7SKP204, and TRAJ11. Each is linked with MEF2B in more than 1 cancer types. Because this analysis shows association rather than direction, both MEF2B-to-partner and partner-to-MEF2B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MEF2B→partner) and Y-score (partner→MEF2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUSCRNA5SP281 →+0.254+5.625<.001.00432
UCECRN7SKP204 →+0.221+2.523.007.00832
UCECTRAJ11 →+0.696+2.620<.001<.00132
SKCMRNU4-84P →+0.098+3.990<.001.00932
BLCAMIR1231 →+0.318+7.640<.001.00932
HNSCODF1 →+0.120+4.010<.001.00631
Each partner links to its Q-omics profile. Showing the 6 strongest of 428 associations by consensus.

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