MED8

Across TCGA patient cohorts, MED8 protein abundance is significantly associated with the RNA expression of many other genes, with 15,132 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MED8-associated genes across cancer lineages are UNG, ATAD2, and UBQLN4. Each is linked with MED8 in more than 7 cancer types. Because this analysis shows association rather than direction, both MED8-to-partner and partner-to-MED8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MED8 versus UNG in LSCC, with a Pearson correlation of 0.66.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MED8→partner) and Y-score (partner→MED8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	UNG →	+0.927	+0.362	<.001	<.001	3	8
BRCA	ATAD2 →	+0.767	+0.219	.001	<.001	3	7
LUAD	UBQLN4 →	+0.630	+0.199	<.001	<.001	3	7
HNSC	CKS1B →	+0.887	+0.119	.001	.002	3	7
HNSC	SUZ12 →	+0.888	+0.196	.001	<.001	3	7
HNSC	LIN9 →	+0.725	+0.153	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,132 associations by consensus.

MED8 vs UNG — LSCC

Explore this scatter interactively →