MED7

Across TCGA cell cohorts, MED7 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,148 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MED7-associated GO terms across cancer lineages are Nucleotide-excision repair, Regulation of centriole elongation, and Granulocyte differentiation. Each is linked with MED7 in more than 10 cancer types. Because this analysis shows association rather than direction, both MED7-to-partner and partner-to-MED7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleotide-excision repair grouped by MED7-low versus MED7-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MED7→partner) and Y-score (partner→MED7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Nucleotide-excision repair →	+0.067	+0.671	.007	.003	3	11
SKIN	Regulation of centriole elongation →	+0.076	+0.752	<.001	<.001	3	10
BLOOD_Myeloma	Granulocyte differentiation →	-0.134	-0.511	.009	.008	3	10
KIDNEY	High-density lipoprotein particle clearance →	-0.189	-0.497	<.001	<.001	3	9
LIVER	Protein localization to site of double-strand break →	+0.101	+0.926	.007	.002	3	9
LUNG_NSCLC_LUAD	Intraciliary transport involved in cilium assembly →	+0.090	+0.464	.006	.004	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,148 associations by consensus.

Nucleotide-excision repair by MED7 expression — LIVER

Explore this box plot interactively →