MED4

Across TCGA patient cohorts, MED4 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,421 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible MED4-associated proteins across cancer lineages are KPNA3, SUGT1, and TSC22D1. Each is linked with MED4 in more than 6 cancer types. Because this analysis shows association rather than direction, both MED4-to-partner and partner-to-MED4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MED4 versus KPNA3 in PDAC, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MED4→partner) and Y-score (partner→MED4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	KPNA3 →	+0.305	+0.321	<.001	<.001	3	7
OV	SUGT1 →	+0.278	+0.528	<.001	<.001	3	7
COAD	TSC22D1 →	+0.479	+0.364	<.001	.001	3	6
GBM	NUDT15 →	+0.587	+0.603	<.001	<.001	3	6
BRCA	GPALPP1 →	+0.430	+0.473	<.001	<.001	3	6
GBM	GTF2F1 →	+0.289	+0.278	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,421 associations by consensus.

MED4 vs KPNA3 — PDAC

Explore this scatter interactively →