MED30

Across TCGA cell cohorts, MED30 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,262 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible MED30-associated GO terms across cancer lineages are G2/M transition of mitotic cell cycle, Positive regulation of cell cycle process, and Protein localization to condensed chromosome. Each is linked with MED30 in more than 10 cancer types. Because this analysis shows association rather than direction, both MED30-to-partner and partner-to-MED30 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, G2/M transition of mitotic cell cycle grouped by MED30-low versus MED30-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MED30→partner) and Y-score (partner→MED30) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	G2/M transition of mitotic cell cycle →	+0.109	+0.947	<.001	<.001	3	11
BREAST	Positive regulation of cell cycle process →	+0.074	+0.973	<.001	.001	3	11
UPPER_AERODIGESTIVE_TRACT	Protein localization to condensed chromosome →	+0.101	+0.696	.008	.003	3	11
UPPER_AERODIGESTIVE_TRACT	Protein localization to kinetochore →	+0.147	+0.730	<.001	.006	3	10
KIDNEY	Cell cycle G2/M phase transition →	+0.097	+0.879	<.001	.001	3	10
LUNG_NSCLC_LUSC	Positive regulation of DNA-directed DNA polymerase activity →	+0.162	+1.068	.007	.002	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,262 associations by consensus.

G2/M transition of mitotic cell cycle by MED30 expression — KIDNEY

Explore this box plot interactively →