Q-omics provides the consensus-scored MED28P3 profile across patient tissues and cancer cell-line models. MED28P3 expression is associated with patient survival in 23 of 34 cancer types, with the highest sampling consensus in HNSC. Among the 18 cancer types available for tumor–normal comparison, MED28P3 is differentially expressed in 3, with the highest sampling consensus in KICH. Additionally, MED28P3 RNA expression shows 17,295 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight HNSC, KICH, and THYM as cancer lineages where MED28P3 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MED28P3 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MED28P3 survival associations across molecular data types. MED28P3 RNA expression shows survival associations in the most cancer types (23). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MED28P3 RNA expression–survival associations across cancer types. High MED28P3 expression shows favorable associations in HNSC, KIRC, MESO, ACC, LUSC and STAD. The HNSC Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify HNSC as the clearest survival context for MED28P3 RNA expression.
This table summarizes MED28P3 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 3. The strongest signals are observed in KICH for RNA.
This table ranks reproducible tumor–normal expression differences for MED28P3. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MED28P3 shows lower tumor expression in KICH, THCA and KIRC. The KICH box plot shows higher MED28P3 RNA expression in normal versus tumor tissue (log2 FC = −0.601, t-test p < 0.001).
This table shows molecular features associated with MED28P3 in patient tissues and cancer cell lines. In patient samples, MED28P3 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
