MED26

Across TCGA cell cohorts, MED26 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,272 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MED26-associated GO terms across cancer lineages are Negative regulation of protein localization to chromatin, Mitotic chromosome condensation, and Regulation of protein localization to chromatin. Each is linked with MED26 in more than 15 cancer types. Because this analysis shows association rather than direction, both MED26-to-partner and partner-to-MED26 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of protein localization to chromatin grouped by MED26-low versus MED26-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MED26→partner) and Y-score (partner→MED26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of protein localization to chromatin →	+0.157	+0.633	<.001	.001	3	16
BONE	Mitotic chromosome condensation →	+0.177	+0.584	<.001	<.001	3	15
URINARY_TRACT	Regulation of protein localization to chromatin →	+0.128	+0.641	.001	<.001	3	14
SOFT_TISSUE	Positive regulation of T-helper 17 cell lineage commitment →	+0.178	+0.546	<.001	<.001	3	14
PANCREAS	Negative regulation of transcription initiation by RNA polymerase II →	+0.130	+0.648	<.001	<.001	3	13
BONE	Positive regulation of anaphase-promoting complex-dependent catabolic process →	+0.234	+0.876	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,272 associations by consensus.

Negative regulation of protein localization to chromatin by MED26 expression — BONE

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