MED23

Across TCGA patient cohorts, MED23 protein abundance is significantly associated with the RNA expression of many other genes, with 17,820 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MED23-associated genes across cancer lineages are MTFR2, LIN9, and TRIP13. Each is linked with MED23 in more than 6 cancer types. Because this analysis shows association rather than direction, both MED23-to-partner and partner-to-MED23 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MED23 versus MTFR2 in BRCA, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MED23→partner) and Y-score (partner→MED23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MTFR2 →	+0.708	+0.224	.004	.002	3	7
BRCA	LIN9 →	+0.708	+0.253	<.001	<.001	3	7
LSCC	TRIP13 →	+0.887	+0.218	<.001	<.001	3	7
GBM	VRK1 →	+0.815	+0.343	<.001	<.001	3	6
BRCA	MYBL2 →	+1.274	+0.263	.001	<.001	3	6
LSCC	FAM83D →	+1.037	+0.178	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,820 associations by consensus.

MED23 vs MTFR2 — BRCA

Explore this scatter interactively →