MED21

Across TCGA patient cohorts, MED21 protein abundance is significantly associated with the RNA expression of many other genes, with 6,572 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MED21-associated genes across cancer lineages are CCRL2, SRPX2, and FKBP14. Each is linked with MED21 in more than 3 cancer types. Because this analysis shows association rather than direction, both MED21-to-partner and partner-to-MED21 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MED21 versus CCRL2 in OV, with a Pearson correlation of -0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MED21→partner) and Y-score (partner→MED21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CCRL2 →	-0.745	-0.368	.001	.001	3	4
COAD	SRPX2 →	-0.987	-0.257	.001	<.001	3	3
OV	FKBP14 →	-0.795	-0.370	.001	<.001	3	3
BRCA	CCDC34 →	+0.691	+0.253	<.001	<.001	3	3
LSCC	SUDS3 →	+0.442	+0.259	.002	.002	3	3
OV	NID1 →	-1.155	-0.343	.002	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,572 associations by consensus.

MED21 vs CCRL2 — OV

Explore this scatter interactively →