MED20

Across TCGA patient cohorts, MED20 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,904 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MED20-associated proteins across cancer lineages are XPO5, ZNF318_S709, and ZNF318. Each is linked with MED20 in more than 8 cancer types. Because this analysis shows association rather than direction, both MED20-to-partner and partner-to-MED20 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MED20 versus XPO5 in LSCC, with a Pearson correlation of 0.76.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MED20→partner) and Y-score (partner→MED20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	XPO5 →	+0.687	+0.755	<.001	<.001	3	9
PDAC	ZNF318_S709 →	+0.626	+0.500	<.001	<.001	3	8
GBM	ZNF318 →	+0.406	+0.539	<.001	<.001	3	7
GBM	PPM1G →	+0.541	+0.380	<.001	<.001	3	6
OV	GNL1 →	+0.332	+0.447	<.001	.001	3	6
GBM	SRPK1_S51 →	+0.653	+0.365	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,904 associations by consensus.

MED20 vs XPO5 — LSCC

Explore this scatter interactively →