MED17

Across TCGA cell cohorts, MED17 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,333 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MED17-associated GO terms across cancer lineages are Regulation of protein acetylation, Positive regulation of protein acetylation, and Microtubule organizing center organization. Each is linked with MED17 in more than 15 cancer types. Because this analysis shows association rather than direction, both MED17-to-partner and partner-to-MED17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein acetylation grouped by MED17-low versus MED17-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MED17→partner) and Y-score (partner→MED17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Regulation of protein acetylation →	+0.128	+0.715	<.001	.002	3	16
BREAST	Positive regulation of protein acetylation →	+0.111	+0.926	<.001	<.001	3	16
SOFT_TISSUE	Microtubule organizing center organization →	+0.084	+0.666	<.001	<.001	3	15
SOFT_TISSUE	Centrosome cycle →	+0.089	+0.715	<.001	<.001	3	14
BONE	Centrosome duplication →	+0.133	+0.617	.002	.004	3	14
LUNG_SCLC	Regulation of centrosome duplication →	+0.129	+0.841	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,333 associations by consensus.

Regulation of protein acetylation by MED17 expression — STOMACH

Explore this box plot interactively →