MED11

Across TCGA cell cohorts, MED11 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,680 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MED11-associated GO terms across cancer lineages are Regulation of synaptic transmission, dopaminergic, Glycine biosynthetic process, and Adult walking behavior. Each is linked with MED11 in more than 11 cancer types. Because this analysis shows association rather than direction, both MED11-to-partner and partner-to-MED11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of synaptic transmission, dopaminergic grouped by MED11-low versus MED11-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MED11→partner) and Y-score (partner→MED11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Regulation of synaptic transmission, dopaminergic →	+0.266	+0.985	.001	.001	3	12
URINARY_TRACT	Glycine biosynthetic process →	+0.243	+0.956	<.001	.004	3	10
URINARY_TRACT	Adult walking behavior →	+1.229	+0.948	<.001	<.001	3	10
URINARY_TRACT	Polyamine acetylation →	+0.207	+0.836	<.001	<.001	3	10
URINARY_TRACT	Spermidine acetylation →	+0.207	+0.836	<.001	<.001	3	10
BLOOD_Leukemia	Positive regulation of establishment of protein localization to telomere →	-0.044	-0.626	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,680 associations by consensus.

Regulation of synaptic transmission, dopaminergic by MED11 expression — URINARY_TRACT

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